April 17, 2024
Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach

Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach

Because the emergence of novel Coronavirus (SARS-CoV-2) an infection in Wuhan, China in December 2019, it has now unfold to over 205 international locations. The ever-growing checklist of worldwide unfold corona virus-19 illness (COVID-19) sufferers has demonstrated the excessive transmission charge among the many human inhabitants. At the moment, there aren’t any FDA authorised medication or vaccines to stop and deal with the an infection of the SARS-CoV-2. Contemplating the present state of affairs, there’s an pressing unmet medical must determine novel and efficient approaches for the prevention and remedy of COVID-19 by re-evaluating the information of conventional medicines and repurposing of medicine.

Right here, we used molecular docking and molecular dynamics simulation strategy to discover the useful roles of phytochemicals and lively pharmacological brokers current within the Indian herbs that are broadly used within the preparation of Ayurvedic medicines within the type of Kadha to regulate varied respiratory issues reminiscent of cough, chilly and flu. Our research has recognized an array of phytochemicals current in these herbs which have important docking scores and potential to inhibit completely different phases of SARS-CoV-2 an infection in addition to different Coronavirus goal proteins.

The phytochemicals current in these herbs possess important anti-inflammatory property. Other than this, primarily based on their pharmaceutical traits, we’ve got additionally carried out in-silico drug-likeness and predicted pharmacokinetics of the chosen phytochemicals discovered within the Kadha. Total our research offers scientific justification by way of binding of lively substances current in numerous crops utilized in Kadha preparation with viral proteins and goal proteins for prevention and remedy of the COVID-19. Communicated by Ramaswamy H. Sarma.

Biomarker Evaluation Primarily based Chemoprofiling of Polyherbal Ayurvedic Formulation Containing Vitis vinifera L. by Validated UPLC-MS/MS Technique

Background: Drakshasava is among the business Ayurvedic medication from India, ready from grapes and spices. It’s believed to deal with well being imbalances and claimed to be useful for weak point bleeding issues and varied inflammatory ailments. It reported pharmacological actions reminiscent of diuretic, cardioprotective and antimicrobial. Being a polyherbal combination, it faces challenges in its standardization and high quality management. Goal The intention of the current research is to develop a validated UPLC-MS/MS methodology for simultaneous quantification of ten polyphenolic biomarkers in Drakshasava. It explores the impact of Vitis vinifera L. and extra herbs on fermentation with respect to bioactive compounds via successive addition methodology.
Technique: The MS strategies have been optimized in multiple-reaction monitoring (MRM) mode with ESI whereas chromatographic separation was achieved on an Acquity UPLC BEH C18 column utilizing each isocratic and gradient elution in water and acetonitrile containing 0.1% formic acid.
Outcomes: The developed methodology was validated as per ICH-Q2B tips and located to be throughout the assay variability limits. Gallic acid was discovered to be essentially the most considerable marker in all of the samples adopted by resveratrol. The content material of all of the markers has discovered to be elevated considerably submit fermentation, in comparison with decoction besides kaempferol. The successive addition of prashpeka drvya (minor herbs) within the formulation, present variability at completely different phases, with respect to the chosen markers and doesn’t infer main adjustments within the chemical profiling of ultimate product.
Conclusion: The developed methodology was discovered fast, correct, dependable and extremely delicate for the simultaneous quantification of chosen biomarkers in Drakshasava. The analysis is the primary chemometric report in standardization of Drakshasava by validated UPLC-MS/MS methodology. It might show to be useful gizmo for growth of recent phyto-pharmaceutical drug and additional high quality management of different poly natural formulations.
 Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach
Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach

Immunoprotective potential of Ayurvedic herb Kalmegh (Andrographis paniculata) in opposition to respiratory viral infections – LC-MS/MS and community pharmacology evaluation

Introduction: Immunity boosting has emerged as a worldwide technique to combat the SARS-CoV-2 pandemic scenario. In India, AYUSH methods of medication have been promoted as an immune-protection technique. Andrographis paniculata (Burm. F) Nees (AP) talked about in Ayurveda has been broadly used for treating sore throat, flu, and higher respiratory tract infections which can present potential novel therapeutic approaches, completely focusing on SARS-CoV-2 and its pathways.
Targets: The current work makes use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) metabolomics and mixture synergy evaluation primarily based on community pharmacology to mine multimode proof to grasp the potential mechanism of motion, ailments affiliation, protein-protein interplay and main pathways concerned therein.
Materials and strategies: Metabolite profiling was carried out by Agilent QTOF LC-MS/MS system. Community pharmacology evaluation was carried out through the use of useful annotation evaluation primarily based on databases like Binding DB, STRING, DAVID and KEGG for additional knowledge mining. Additional mixture synergy was evaluated utilizing “neighbourhood strategy” and networks have been constructed via Cytoscape 3.2.1.

Anti-Mouse Podoplanin Antibody

103-M552 100 µg
EUR 399
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Mouse Podoplanin Antibody

103-PA40 200 µg
EUR 204.75
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Mouse Podoplanin Antibody

103-PA40S 100 µg
EUR 126
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Mouse Podoplanin ELISA kit

E01A24381 96T
EUR 700
Description: ELISA

Mouse Podoplanin ELISA kit

E03P0082-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA Kit

IMSPDPNKT each
EUR 752
Description: Mouse Podoplanin ELISA Kit

anti- Podoplanin antibody

FNab06598 100µg
EUR 702
Description: Antibody raised against Podoplanin

anti- Podoplanin antibody

FNab06599 100µg
EUR 702
Description: Antibody raised against Podoplanin

Mouse Monoclonal anti-Rat Podoplanin Antibody

xAP-0897 100ug
EUR 280

Mouse Podoplanin (PDPN) Protein

20-abx650139
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  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Podoplanin (PDPN) Protein

abx694266-10nmol 10 nmol
EUR 700

Mouse Podoplanin (PDPN) Protein

abx694266-5nmol 5 nmol
EUR 462.5

Mouse Podoplanin (PDPN) Protein

abx650139-100g 100 µg
EUR 537.5

Mouse Podoplanin (PDPN) Protein

abx650139-10g 10 µg
EUR 212.5

Mouse Podoplanin (PDPN) Protein

abx650139-50g 50 µg
EUR 375

Mouse Monoclonal Podoplanin Antibody

TA327727 1 ml Ask for price

Mouse Podoplanin (PDPN) CLIA Kit

20-abx493858
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu 96T
EUR 475
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

EK8596 96Т
EUR 799

Mouse Podoplanin, Pdpn ELISA KIT

ELI-06723m 96 Tests
EUR 1038

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-48T 48T
EUR 389.62

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-5x96T 5x96T
EUR 2643.85

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-96T 96T
EUR 556.6

Mouse Podoplanin (PDPN) ELISA Kit

EKU06727-48T 48T
EUR 571.55

Mouse Podoplanin (PDPN) ELISA Kit

EKU06727-5x96T 5x96T
EUR 3878.38

Mouse Podoplanin (PDPN) ELISA Kit

EKU06727-96T 96T
EUR 816.5

Mouse Podoplanin (PDPN) ELISA Kit

DL-PDPN-Mu 96T
EUR 453
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

abx571749-96tests 96 tests
EUR 943.2

Mouse Podoplanin (PDPN) ELISA Kit

AE28131MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Podoplanin (PDPN) ELISA Kit

AE28131MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse Podoplanin (PDPN) ELISA Kit

20-abx154564
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-48T 48T
EUR 464.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-48Tests 48 Tests
EUR 639.6

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-96T 96T
EUR 663.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-96Tests 96 Tests
EUR 888

Mouse Podoplanin (PDPN) ELISA Kit

RK13459 96T
EUR 280

Mouse Podoplanin(PDPN)ELISA kit

QY-E21215 96T
EUR 433.2

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

4-SEC719Mu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-48T 48T
EUR 487.52
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-48Tests 48 Tests
EUR 668.4

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-96T 96T
EUR 696.47
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-96Tests 96 Tests
EUR 928.8

Mouse Podoplanin (PDPN)ELISA kit

YLA0596MO-48T 48T Ask for price

Mouse Podoplanin (PDPN)ELISA kit

YLA0596MO-96T 96T Ask for price

Mouse PDPN(Podoplanin) ELISA Kit

ELK7080-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPN. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PDPN, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PDPN in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PDPN(Podoplanin) ELISA Kit

ELK7080-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPN. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PDPN, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PDPN in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PDPN (Podoplanin) ELISA Kit

EKE61859-5x96T 5x96T
EUR 3124.08

Mouse PDPN (Podoplanin) ELISA Kit

EKE61859-96T 96T
EUR 657.7

Mouse PDPN(Podoplanin) ELISA Kit

RE2052M-48wells 48 wells
EUR 116.55

Mouse PDPN(Podoplanin) ELISA Kit

RE2052M-96wells 96 wells
EUR 161.55

Mouse Pdpn / Podoplanin ELISA Kit

E2095m 96T
EUR 776

Anti-Rat Podoplanin Antibody

104-M40 100 µg
EUR 189
Description: Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. It was originally discovered in kidney podocytes. This mouse monoclonal antibody (IgG) against rat podoplanin works well for immunohistochemistry with formalin-fixed paraffin embedded sections. This antibody also can be used in FACS sorting.

Anti- Podoplanin Human Antibody

GWB-F131C7 0.2 mg Ask for price

Podoplanin

E8ER1915-23 100ul
EUR 275
Description: Available in various conjugation types.

Podoplanin

E8ET1703-61 100ul
EUR 275
Description: Available in various conjugation types.

Podoplanin

AP79286 1mg
EUR 2640

Podoplanin

AP86601 1mg
EUR 2640

Podoplanin

AP87092 1mg
EUR 2640

Podoplanin

AP87543 1mg
EUR 2640

Podoplanin

MO47016 100 ul
EUR 418.8

Rabbit Anti-Human Podoplanin

102-PA40 100ug
EUR 240

Recombinant Mouse Podoplanin (C-Fc)

CU73-10ug 10ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-1mg 1mg
EUR 2008.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-500ug 500ug
EUR 1399.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-50ug 50ug
EUR 327.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Podoplanin, PDPN GENLISA ELISA

KLM1437 1 x 96 wells
EUR 341

Anti-Human Podoplanin Antibody

102-PA40AG 50 µg
EUR 147
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver (1). Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

102-PA40S 100 µg
EUR 126
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential O-linked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on O-glycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

101-M40-FITC 50 µg Ask for price
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

101-M40-PE 50 µg Ask for price
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

101-M40S-FITC 25 µg Ask for price
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

101-M40S-PE 25 µg Ask for price
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Human Podoplanin Antibody

101-M41 100 µg
EUR 199.5
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential O-linked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on O-glycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Hamster Monoclonal anti-mouse Podoplanin

mAP-0062 100ug
EUR 250

Podoplanin (PDPN) Polyclonal Antibody (Mouse)

4-PAC719Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN)

ELISA kit for Mouse Podoplanin (PDPN)

KTE70775-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Podoplanin (PDPN)

KTE70775-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Podoplanin (PDPN)

KTE70775-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse PDPN (Podoplanin)

E-EL-M2409 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse PDPN (Podoplanin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse PDPN (Podoplanin)

ELK7080 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Podoplanin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Podoplanin antibody

10R-7662 100 ug
EUR 754.8
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-7663 100 ug
EUR 754.8
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody

10R-7664 100 ug
EUR 754.8
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-P133a 100 ug
EUR 438
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-P155a 100 ug
EUR 468
Description: Hamster monoclonal Podoplanin antibody

Podoplanin Antibody

E38PA2500 100ul
EUR 225
Description: Available in various conjugation types.

Podoplanin Antibody

DF12456 200ul
EUR 420

Podoplanin Antibody

DF12456-100ul 100ul
EUR 280

Podoplanin Antibody

DF12456-200ul 200ul
EUR 350

Podoplanin Antibody

49474 100ul
EUR 499

Podoplanin Antibody

49474-100ul 100ul
EUR 399.6

Podoplanin Antibody

49474-50ul 50ul
EUR 286.8

Podoplanin antibody

70R-PR007 100 ug
EUR 524
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody

70R-13952 100 ug
EUR 484
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody

70R-11540 100 ug
EUR 632.4
Description: Rabbit polyclonal Podoplanin antibody

Podoplanin antibody

70R-6816 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN

Podoplanin antibody

70R-6817 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN

Podoplanin antibody

70R-50819 100 ul
EUR 242
Description: Purified Polyclonal Podoplanin antibody

Podoplanin Antibody

GWB-9E8999 1 ml Ask for price

Podoplanin Antibody

GWB-61B370 0.1 mg Ask for price

Podoplanin Antibody

R20464-0.1ML 100ul
EUR 409

Podoplanin Antibody

R33852-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: PDPN; AGGRUS; GP36; GP40; Gp38; HT1A-1; OTS8; PA2.26

Podoplanin Antibody

P1051-01m 0.1m
EUR 250.8

Podoplanin Antibody

P1051-1ml 1ml
EUR 1129.2

Anti-D2-40 Podoplanin antibody

STJ16100360 1 mL
EUR 1482

Anti-D2-40/Podoplanin antibody

STJ190048 200 µl
EUR 236.4
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)

Podoplanin (PDPN) Polyclonal Antibody (Mouse), PE

4-PAC719Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with PE.

Pdpn (untagged) - Mouse podoplanin (Pdpn), (10ug)

MC201786 10 µg Ask for price

Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC

4-PAC719Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), Cy3

4-PAC719Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Cy3.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), HRP

4-PAC719Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with HRP.

Podoplanin Mouse Monoclonal Antibody (IHC Gold)

E44H20290 250ul
EUR 655
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rat Monoclonal anti-Mouse Podoplanin Antibody

xAP-0812 100ug
EUR 280

Podoplanin (PDPN) Polyclonal Antibody (Mouse), FITC

4-PAC719Mu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with FITC.

Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761

CABT-L2919-100uL500uL 100 uL, 500 uL
EUR 602.4

Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761

CABT-L2919 100 µl, 500 µl Ask for price
Description: Mouse

Mouse Podoplanin, soluble Recombinant Protein

S01-M46 5 µg
EUR 63
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Podoplanin (PDPN) Antibody

abx433110-200ul 200 ul
EUR 460.8

Podoplanin (PDPN) Antibody

20-abx339428
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  • 100 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx129101
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Podoplanin (PDPN) Antibody

20-abx131102
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Podoplanin (PDPN) Antibody

20-abx211099
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  • 100 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx174125
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  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx174126
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  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx178065
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  • 1 mg
  • 200 ug
Outcomes: The molecules from kalmegh offers immune-protection and anti-viral response through involving completely different pathways, like toll-like receptor pathway, PI3/AKT pathway and MAP kinase pathways in opposition to COVID-19 an infection. The KEGG evaluation confirmed that in a overwhelming majority of essentially the most enriched pathways, AP have been related to viral infections and higher respiratory tract infections.

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